Anti-Cancer Influence Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) can be a Vietnamese traditionally medicinal plant utilized in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to analyze the end results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data demonstrate that using methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly modify the phytochemical compounds and biological activity from plant materials. The aims on this study could determine the effects of different drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The outcome demonstrated that microwave drying was a highly effective method in eliminating water when it comes to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity from your P. trimera root while methanol and microwave-assisted extraction were the very best solvent and way of greatest extraction of the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings out of this study allow retaining the highest amounts of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application from the nutraceutical industry.


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