Anti-Cancer Impact Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Breast Cancer

Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is really a Vietnamese traditionally medicinal plant found in the treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to analyze the end results of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the greatest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (aside from total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data reveal that using methanol and microwave-assisted extraction are recommended for extraction of biologically active phytochemicals from P. trimera root for application inside the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims on this study would determine the consequences of various drying methods, various solvents and extraction methods about the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root purchased from Vietnam. The outcome demonstrated that microwave drying was an effective method in removal of water with regards to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the very best solvent and way of greatest extraction of the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings because of this study allow retaining the highest degrees of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application in the nutraceutical industry.


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